Comparison between the accuracy of a rapid point-of-care HIV test TOYO versus ELISA, Western Blot, and RT-PCR analysis

Background: The human immunodeficiency virus (HIV) is considered one of the most serious health challenges worldwide. Early detection and diagnosis are key elements in the effort to control HIV. Rapid tests for the detection of HIV-antibody allow timely point-of-care provision of results and do not require the laboratory facilities needed for conventional enzyme immunoassays (enzyme-linked immunosorbent assay [ELISA]) and Western blot (WB) testing. Regardless of the advantages of these tests, other studies showed that the sensitivity of the performance of some rapid test brands comparing with the lab standard methods have some limitation.